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  • Holin - Wikipedia
    Holin Holins are a diverse group of small proteins produced by dsDNA bacteriophages in order to trigger and control the degradation of the host's cell wall at the end of the lytic cycle
  • Holins: the protein clocks of bacteriophage infections
    Holins are small membrane proteins that accumulate in the membrane until, at a specific time that is "programmed" into the holin gene, the membrane suddenly becomes permeabilized to the fully folded endolysin
  • Bacteriophage-encoded lethal membrane disruptors: Advances in . . .
    Examples include the class I holin S105 of lambda and the class II holin S 21 68 of lambdoid bacteriophage ϕ21 (Smith et al , 1998) These two classes of holins are the most abundant holins described in bacteriophages so far
  • Holins in Bacteria, Eukaryotes, and Archaea . . . - eScholarship
    holin gene in vivo, first in a human breast cancer cell tumor xenograft and second in a mammary a enocarcinoma mouse model system When the holin was inducibly expressed, a reduction in tumor cell viability by up to 98% resulted Thus, lam
  • Holin - Wikiwand
    Diverse group of small proteins From Wikipedia, the free encyclopedia Holins are a diverse group of small proteins produced by dsDNA bacteriophages in order to trigger and control the degradation of the host's cell wall at the end of the lytic cycle
  • Holin – Knowledge and References – Taylor Francis
    A holin is a protein that accumulates and oligomerizes in the cytoplasmic membrane in a time-controlled manner, triggering depolarization and the formation of holes in the membrane
  • Spatial and temporal control of lysis by the lambda holin - PMC
    Here, we investigate the molecular basis of polar lysis using time-lapse fluorescence microscopy The results indicate that the holin determines the morphology of lysis by suddenly forming two-dimensional rafts at the poles about 100 s prior to lysis
  • Bacteriophage-encoded protein utilization in bacterial ghost production . . .
    This review comprehensively surveys the utilization of phage-encoded proteins in BG production techniques, encompassing methodologies such as phage E protein-mediated lysis, perforin protein-induced lysis, and strategies combining E protein with holin-endolysin systems





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