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  • Equine Protozoal Myeloencephalitis (EPM) Testing
    The reluctance to perform a spinal tap due to risk, cost or inexperience is understandable and although not the preferred approach, a positive serum IgG test in the presence of neurologic signs and history compatible with EPM, supports a diagnosis of EPM
  • Tips for Diagnosing EPM in Horses - EquiManagement
    Diagnosing equine protozoal myeloencephalitis (EPM) is complicated by the high prevalence of exposure and low prevalence of disease Serology is often the first-line test, but the best use of serology is its negative predictive value
  • Equine Protozoal Myeloencephalitis (EPM) - School of Veterinary Medicine
    A positive blood test only determines that the horse has been exposed to the parasite and does not mean that the horse will develop clinical signs or that the neurological deficits are caused by the protozoal parasite
  • Blood Testing for EPM in Horses - Veterinary Partner - VIN
    However, none of these horses had any symptoms of EPM and were normal It is important to realize that only less than one percent of horses found to be positive on blood test are actually going to show symptoms of the disease
  • Equine Protozoal Myeloencephalitis - MSD Veterinary Manual
    Horses with EPM involving the spinal cord can have asymmetric or symmetric weakness and ataxia in any number of limbs, sometimes with obvious muscle atrophy that may be most easily noted in the epaxial or gluteal regions
  • 5 Points to Help Veterinarians Diagnose EPM - The Horse
    Equine protozoal myeloencephalitis (EPM) is a common neurologic disease that affects horses throughout the United States However, it remains challenging to definitively diagnose
  • Equine protozoal myeloencephalitis (EPM)
    The presence of antibodies can help support a diagnosis of EPM when horses display signs of illness but, alone, a positive blood test does not confirm a diagnosis
  • Equine Protozoal Myeloencephalitis (EPM) in Horses by a Vet – 2025 . . .
    With multiple lookalike illnesses, incomplete testing options, and expensive treatment, EPM demands a thoughtful diagnostic process In this guide, Dr Duncan Houston explains how to distinguish EPM from other diseases, test accurately, treat effectively, and prevent exposure
  • EPM in Horses: Early Signs, Diagnosis Management
    Blood alone is not proof of EPM; many horses have been exposed If signs and exam findings point to the spinal cord, the vet may prioritize CSF (cerebrospinal fluid) testing because antibodies in CSF indicate local immune activity and are generally more specific than blood
  • Equine Protozoal Myeloencephalitis Practice Tips
    For a horse to be considered as an EPM suspect, they MUST have neurologic deficits! Neurologic deficits from EPM are classically multifocal, and associated with asymmetric muscle atrophy, but they can be ANYWHERE and do ANYTHING within the CNS





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