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  • Satellite and Tandem DNA Repeats in the Human Genome
    Satellite DNA comprises long arrays of tandem DNA repeats with moderate to long length, that account for the majority of heterochromatic sequences of the human genome, organizing centromeric, paracentromeric, and acrocentric regions of eukaryotic chromosomes, as well as the human Y chromosome
  • A classical revival: Human satellite DNAs enter the genomics era
    The classical human satellite DNAs, also referred to as human satellites 1, 2 and 3 (HSat1, HSat2, HSat3, or collectively HSat1–3), occur on most human chromosomes as large, pericentromeric tandem repeat arrays, which together constitute roughly 3% of the human genome (100 megabases, on average)
  • Alpha satellite DNA biology: Finding function in the recesses of the . . .
    Satellite DNA was first identified in the 1970s as a distinct low-density buoyancy band that separated from bulk genomic DNA in cesium chloride density gradients (Yasmineh and Yunis, 1974) This class of DNA encompasses many types of highly repetitive tandem repeats
  • Satellite DNAs rising from the transposon graveyards | DNA Research . . .
    We summarize various mechanisms regarding the generation of satDNAs from TEs Notably, we present a hypothesis that seeks to explain the existence of satDNA sequences that share short stretches of similarity with multiple TEs, suggesting that these satDNA sequences may originate from ‘TE graveyards’ 2 Evolutionary significance of satDNAs
  • TaqMan基因表达检测设计指南-赛默飞 | Thermo Fisher Scientific - CN
    Designing a TaqMan assay is a crucial step in accurately quantifying gene expression with exceptional specificity and sensitivity TaqMan assays leverage fluorescent probes to detect and measure specific nucleic acid sequences, making them a highly reliable tool for real-time PCR (qPCR) research
  • A classical revival: Human satellite DNAs enter the genomics era
    Satellite DNA arrays can be classified into distinct families based on both their sequence composition, which is often AT-rich overall, and on their characteristic repeat unit lengths, which range from several bases to kilobases
  • De novo reconstruction of satellite repeat units from sequence data . . .
    Applying SRF to real sequence data, we show that SRF could reconstruct known satellites in human and well-studied model organisms We also find satellite repeats are pervasive in various other species, accounting for up to 12% of their genome contents but are often underrepresented in assemblies
  • Sequence, Chromatin and Evolution of Satellite DNA - MDPI
    Here we describe the different classes of satellite DNA sequences, their satellite-specific chromatin features, and how these features may contribute to satellite DNA biology and evolution





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